Lj. Vanbogaert, SPINAL-BLOCK CESAREAN-SECTION IN PARTURIENTS WITH PREGNANCY-INDUCED HYPERTENSION, East African medical journal, 75(4), 1998, pp. 227-231
The objective of this work was to determine whether parturients with p
regnancy-induced hypertension (PIH) are at higher risk of post-spinal
hypotension at caesarean section. This was an observational study of 2
4 women with PIH undergoing caesarean section under spinal analgesia w
ith 0.5% hyperbaric bupivaeaine, compared with 24 matched normotensive
parturients receiving a spinal block for caesarean section. The mean
intraoperative systolic arterial pressure (SAP) was similar with and w
ithout PIH (p=0.38), The mean percentage decrease in SAP of baseline w
as more with PIH (16.2%) than in the controls (0.5%)(p<0.001). The num
ber of episodes of severe hypotension (SAP decrease to less than or eq
ual to 80% of baseline and < 90 mmHg)(p=0.80) as well as the magnitude
(p=0.31) of severe hypotension was similar in both groups. There was
no difference in the evolution of diastolic arterial pressure and mate
rnal pulse rate between cases and controls. Maximum levels of upper se
nsory blockade were similar. Foetal and maternal outcome was similar w
ith and without PIH. The decrease in SAP is less on an absolute scale
but more on a percentile basis with PIH at caesarean section under spi
nal analgesia than in normotensive patients. The difference, however,
is not clinically sufficient to discourage spinal analgesia for caesar
ean section with a low dose ( 1.5 mi, 7.5 mg) of 0.5% hyperbaric bupiv
acaine in parturients with PIH.