U. Alberg et Cc. Mullergoymann, INFLUENCE OF ETHANOL ON MICROSTRUCTURE AND TECHNOLOGICAL PROPERTIES OF UNGUENTUM-EMULSIFICANS-AQUOSUM DAB-1997, Die Pharmazie, 53(9), 1998, pp. 631-634
Water containing hydrophilic ointment was modified by incorporation of
ethanol. The influence on the microbiological situation and on the co
oling effect of the vehicle was investigated. An amount of 10% (m/m) h
ad an antimicrobiological activity. The cooling effect decreased with
an increasing amount of ethanol so we suppose an incorporation of the
ethanol in the interlamellar network of the cream.