D. Jirovsky et al., METHAMPHETAMINE - PROPERTIES AND ANALYTICAL METHODS OF ENANTIOMER DETERMINATION, Forensic science international, 96(1), 1998, pp. 61-70
Methamphetamine is one of the most frequently abused drugs of today. D
ue to its stereogenic center, it can exist as single enantiomer. Like
many other chiral compounds, methamamphetamine enantiomers exhibit dif
ferent pharmacological effects on living organisms. For this reason, i
t is necessary to develop enantioselective and sufficiently sensitive
methods of determination. This review focuses on methamphetamine with
an accent on analytical chemistry and especially on chiral separations
of this toxicologically important compound. (C) 1998 Elsevier Science
Ireland Ltd. All rights reserved.