The appearance in magnetic resonance imaging (MRI) of the bones depend
s, to a large extent on the unmineralized content of the bone cavities
. Because yellow marrow contains a large number of fat protons and red
marrow a significant number of water protons, MRI offers the opportun
ity to map the distribution of red and yellow marrow. In addition, red
marrow MR appearance varies according to the relative proportion of f
at and nonfat cells. Variations in the composition of red marrow and i
ts distribution among normal subjects, mainly in relation to age and s
ex, contribute to creating a wide spectrum in bone MR appearance, whic
h must be known in order to avoid confusion with bone marrow abnormali
ties.