ASYMMETRIC-SYNTHESIS .18. STEREOCONTROLLED SYNTHESIS OF ALPHA-SUBSTITUTED-2-FURFURYLAMINES VIA CHIRAL INTERMEDIATES

Authors
LIU SK MI AQ WU LJ JIANG YZ
Citation
Sk. Liu et al., ASYMMETRIC-SYNTHESIS .18. STEREOCONTROLLED SYNTHESIS OF ALPHA-SUBSTITUTED-2-FURFURYLAMINES VIA CHIRAL INTERMEDIATES, Synthetic communications, 23(17), 1993, pp. 2485-2488
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
17
Year of publication
1993
Pages
2485 - 2488
Database
ISI
SICI code
0039-7911(1993)23:17<2485:A.SSOA>2.0.ZU;2-6
Abstract
The stereocontrolled synthesis of (R)-alpha-alkyl-2-fur furylamines (5 ), using (-)-2-hydroxypinan-3-one (1) as a chiral auxiliary, had been studied. The e. e values of (5) were 91.4 - > 98%, which determined by capillary GC (stationary phase: Chirasil-Val).