Two cases of malignant melanoma (primary and metastatic lesions) image
d with Tc-99m tetrofosmin are reported. One patient showed intense upt
ake in a primary skin lesion of the thorax, and the other patient had
accumulation in skin, cerebellum, breast, and lymph node metastases. L
ike Tc-99m MIBI, Tc-99m tetrofosmin imaging may be of clinical relevan
ce in the evaluation of suspicious skin lesions and in patients with k
nown cutaneous malignant melanoma in the assessment of recurrent disea
se during follow-up evaluation.