LOWERING OF TRIIODOTHYRONINE LEVEL IN BLOOD-PLASMA IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION - RELATIONSHIP WITH EARLY LEFT-VENTRICULAR DILATATION

Levels of triiodothyronine and thyroxine in venous blood were determin ed by radioimmunoassay in 67 patients with Q-wave myocardial infarctio n and results were correlated with data of two-dimensional echocardiog raphy, In all patients these studies were performed on days 10-14 and in 37 patients - on day one of infarction. It was found that in subacu te period of infarction 44,8% of patients had syndrome of euthyroid pa thology (''sick euthyroid syndrome'') with pronounced lowering of trii odothyronine level, normal level of thyroxine, and left ventricular dy sfunction. Formation of this syndrome was related to development of pr edominantly systolic early cardiac dilatation and sustained left ventr icular dysfunction.