SYNTHESIS OF ATOVAQUONE

Authors
WILLIAMS DR CLARK MP
Citation
Dr. Williams et Mp. Clark, SYNTHESIS OF ATOVAQUONE, Tetrahedron letters, 39(42), 1998, pp. 7629-7632
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
42
Year of publication
1998
Pages
7629 - 7632
Database
ISI
SICI code
0040-4039(1998)39:42<7629:>2.0.ZU;2-9
Abstract
A short synthesis of atovaquone 1 is achieved via the radical coupling of the trans-1,4-sbustituted cyclohexyl mono-oxalate 2 and 2-chlorona pthoquinone under phase transfer conditions. (C) 1998 Elsevier Science Ltd. All rights reserved.