A novel antifungal agent, Sch 56036 (1), was isolated from the ferment
ation culture broth of an Actinoplanes sp. Structure elucidation of 1
was accomplished by the analysis of spectroscopic data. Compound 1 was
identified as a new polycyclic xanthone. Biological evaluation of 1 i
ndicated that the compound possesses broad spectrum antifungal activit
y against various yeasts and dermatophytes with geometric mean MIC val
ues ranging from 0.017 similar to 0.031 mu g/mL, respectively. (C) 199
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