A STEREOSPECIFIC SYNTHESIS OF TETRA-SUBSTITUTED CHIRAL PIPERAZINES

Citation
Rj. Abdeljalil et al., A STEREOSPECIFIC SYNTHESIS OF TETRA-SUBSTITUTED CHIRAL PIPERAZINES, Tetrahedron letters, 39(42), 1998, pp. 7703-7704
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
39
Issue
42
Year of publication
1998
Pages
7703 - 7704
Database
ISI
SICI code
0040-4039(1998)39:42<7703:ASSOTC>2.0.ZU;2-K
Abstract
A one pot reaction of the epoxy triflates 1 or 2 with a variety of N,N '-disubstituted ethylenediamines yields the corresponding chiral piper azine derivatives 3a-e and 4a-e of potential pharmacological interest in high yields, (C) 1998 Published by Elsevier Science Ltd. All rights reserved.