ASYMMETRIC-SYNTHESIS OF CHIRAL 2-FLUORINATED 1,3-PROPANEDIOLS AND ITSAPPLICATION TO THE PREPARATION OF MONOFLUORINATED CHIRAL SYNTHON

Authors
YOKOYAMA H HYODO R NAKADA A YAMAGUCHI S HIRAI Y KOMETANI T GOTO M SHIBATA N TAKEUCHI Y
Citation
H. Yokoyama et al., ASYMMETRIC-SYNTHESIS OF CHIRAL 2-FLUORINATED 1,3-PROPANEDIOLS AND ITSAPPLICATION TO THE PREPARATION OF MONOFLUORINATED CHIRAL SYNTHON, Tetrahedron letters, 39(42), 1998, pp. 7741-7744
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
42
Year of publication
1998
Pages
7741 - 7744
Database
ISI
SICI code
0040-4039(1998)39:42<7741:AOC21A>2.0.ZU;2-R
Abstract
Asymmetric synthesis of optically active 2-fluorinated 1,3-propanediol s was achieved by enzymatical resolution and applied to obtain a chira l monofluorinated synthon for lignan derivatives. (C) 1998 Elsevier Sc ience Ltd. All rights reserved.