Ds. Wade et al., ACCURACY OF ULTRASOUND IN THE DIAGNOSIS OF ACUTE APPENDICITIS COMPARED WITH THE SURGEONS CLINICAL IMPRESSION, Archives of surgery, 128(9), 1993, pp. 1039-1046
Objective: To compare the accuracy of the surgeon's clinical diagnosis
of acute appendicitis with that of an ultrasonographic examination of
the abdomen. Design: Prospective trial. Setting: US Naval Hospital, S
an Diego, Calif. Patients: One hundred ten patients admitted to the ho
spital with suspected appendicitis from May 1990 to June 1992. Interve
ntion: Symptoms and signs for each patient were recorded, along with t
he surgeon's clinical impression of immediate surgery or observation.
The patient then underwent an ultrasound examination performed by a st
aff radiologist. On the basis of the ultrasound findings the patient w
as placed into one of three categories: appendicitis, normal examinati
on results, or other conditions. Patients with an ultrasound-based dia
gnosis of appendicitis proceeded to the operation, regardless of the s
urgeon's clinical impression. Those with other conditions diagnosed wi
th ultrasonography were treated as was appropriate for the condition.
Results: The ultrasound-derived diagnosis of appendicitis had a sensit
ivity of 85.5%, a specificity of 84.4%, a positive predictive value of
88.3%, a negative predictive value of 80.1%, and an overall accuracy
of 85.0%. The surgeon's clinical impression at the time of admission h
ad a sensitivity of 62.9%, a specificity of 82.2%, a positive predicti
ve value of 82.9%, a negative predictive value of 61.7%, and an overal
l accuracy of 71.2%. Conclusion: The overall accuracy of ultrasonograp
hy in the diagnosis of appendicitis was statistically superior to that
of the surgeon's clinical impression (P<.0001). However, 24% of the p
atients with normal ultrasound findings were ultimately found to have
appendicitis at operation, emphasizing the point that ultrasonography
cannot be relied on to the exclusion of the surgeon's careful and repe
ated evaluation.