PRIMARY MALIGNANT MIXED MULLERIAN TUMOR OF THE VAGINA

A 74-year-old woman presented with postmenopausal bleeding. Examinatio n showed a 5.5-cm ulcerated, partly necrotic vaginal polyp arising ant eriorly near the hymenal ring. Histology showed a malignant mixed Mull erian tumor (MMMT) with squamous and glandular epithelial and undiffer entiated spindle cell stromal components, cytological atypia, and freq uent mitoses. The tumor was closely associated with overlying vaginal intraepithelial neoplasia, grade III, from which it appeared to be ari sing. The patient was treated by surgical excision, followed by radiot herapy. Six months later, she developed a left supraclavicular lymph n ode metastasis, MMMT is a rare primary vaginal neoplasm, but, includin g this case, there have been at least 7 cases reported in the English language literature. (C) 1998 Academic Press.