PROSPECTS FOR ANXIOLYTIC THERAPY - A REFLECTION FROM DIFFERENT VIEWPOINTS

Authors
MILLET B BAYLE FJ OLIE JP
Citation
B. Millet et al., PROSPECTS FOR ANXIOLYTIC THERAPY - A REFLECTION FROM DIFFERENT VIEWPOINTS, Drug discovery today, 3(10), 1998, pp. 471-479
Citations number
59
Categorie Soggetti
Pharmacology & Pharmacy",Biology
Journal title
Drug discovery today → ACNP
ISSN journal
13596446
Volume
3
Issue
10
Year of publication
1998
Pages
471 - 479
Database
ISI
SICI code
1359-6446(1998)3:10<471:PFAT-A>2.0.ZU;2-J
Abstract
Benzodiazepines are the most commonly used and effective treatment of symptoms of anxiety, but they have drawbacks. The current challenge is to discover partial agonists that do not cause the adverse effects ch aracteristic of benzodiazepines. The authors discuss the main drugs th at are used in the treatment of acute anxiety and some of the current or future alternatives and also highlight several problems that need t o be resolved in the development of new anxiolytics.