NAPHTHOQUINONE ANALOGS AS INACTIVATORS OF CDC25 PHOSPHATASE

Authors
HAM SW PARK J LEE SJ KIM W KANG K CHOI KH
Citation
Sw. Ham et al., NAPHTHOQUINONE ANALOGS AS INACTIVATORS OF CDC25 PHOSPHATASE, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2507-2510
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
18
Year of publication
1998
Pages
2507 - 2510
Database
ISI
SICI code
0960-894X(1998)8:18<2507:NAAIOC>2.0.ZU;2-W
Abstract
cdc25A and cdc25B were significantly overexpressed in certain types of cancers, and they represent potential therapeutic targets for antican cer drug. In this study, naphthoquinone analogs as cdc25A phosphatase inactivators were investigated. (C) 1998 Elsevier Science Ltd. All rig hts reserved.