DESIGN OF NOVEL TRIPEPTIDES WITH MACROPHAGE MIGRATION-ENHANCING ACTIVITY

Authors
NUNAMI K YAMADA M SHIMIZU R
Citation
K. Nunami et al., DESIGN OF NOVEL TRIPEPTIDES WITH MACROPHAGE MIGRATION-ENHANCING ACTIVITY, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2517-2520
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
18
Year of publication
1998
Pages
2517 - 2520
Database
ISI
SICI code
0960-894X(1998)8:18<2517:DONTWM>2.0.ZU;2-O
Abstract
A new approach to the generation of biologically active peptides from non-peptide lead was demonstrated. C,N-ternini protected Phe-Phe-His d erivatives possessing macrophage migration-enhancing activity were des igned on the basis of the structure of imidazoline derivative 1, and t hese structure-activity relationships were also described. (C) 1998 El sevier Science Ltd. All rights reserved.