We have investigated, by fluorescence in situ hybridization (FISH), th
e cytogenetic evolution of the Y chromosome in primates using 17 yeast
artificial chromosomes, representative of the Y-specific euchromatic
region of the human chromosome Y. The FISH experiments were performed
on great apes (Homo sapiens, Pan troglodytes, Gorilla gorilla and Pong
o pygmaeus pygmaeus), and on two Old World monkeys species as an outgr
oup (Cercopitecidae Macaca fascicularis and Papio anubis). The results
showed that this peculiar chromosome has undergone rapid and unconstr
ained evolution both in sequence content and organization.