This study examined whether boys with Fragile X syndrome have a charac
teristic behavioural profile associated with the underlying genetic ab
normality. Parents of 49 boys with Fragile X syndrome, 45 boys with Do
wn's syndrome and 42 boys with intellectual disabilities of unknown ae
tiology were interviewed. Measures included the Childhood Behaviour Ch
ecklist, parent and teacher versions (CBCL), Parental Account of Child
hood Symptoms (PACS) and Vineland social age and social quotient deriv
ed from the MRC Schedule of Handicaps, Behaviour and Skills (HBS).