CHITOSAN - A UNIQUE POLYSACCHARIDE FOR DRUG-DELIVERY

Citation
O. Felt et al., CHITOSAN - A UNIQUE POLYSACCHARIDE FOR DRUG-DELIVERY, Drug development and industrial pharmacy, 24(11), 1998, pp. 979-993
Citations number
125
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
ISSN journal
03639045
Volume
24
Issue
11
Year of publication
1998
Pages
979 - 993
Database
ISI
SICI code
0363-9045(1998)24:11<979:C-AUPF>2.0.ZU;2-Q
Abstract
The aim of this review is to give an insight into the many potential a pplications of chitosan as a pharmaceutical drug carrier The first par t of this review concerns the principal uses of chitosan as an excipie nt in oral formulations (particularly as a direct tableting agent) and as a vehicle for pal-enteral dr-rig delivery devices. The use of chit osan to manufacture sustained-release systems deliverable by other rou tes (nasal, ophthalmic, transdermal, and implantable devices) is discu ssed in the second part.