A sample of 1,038 patients newly admitted to 15 methadone clinics in N
ew York City were studied for up to three years in treatment or until
discharge. Cluster analysis identified distinct patient groups with ve
ry different heroin and cocaine usage patterns during treatment. About
80% either started in or transitioned to a low heroin use group and 5
0% either started in or transitioned to a low cocaine use group during
treatment. One-third of patients used cocaine extensively during trea
tment. Other ''high risk'' groups, such as those not recently employed
, younger, or involved with criminal justice, could benefit from speci
al interventions very early in treatment.