M. Hatori et al., RADIOLOGICAL AND LABORATORY FEATURES OF INFANTILE CORTICAL HYPEROSTOSIS - A CASE-REPORT, International orthopaedics, 22(4), 1998, pp. 272-274
We describe a boy aged nine months with infantile cortical hyperostosi
s in association with cystic fibrosis. Symmetrical periosteal thickeni
ng was present in the clavicles, ribs, femora, humeri, ulnae and radii
. Periosteal hyperostosis of the humerus developed in association with
an increase in the levels of serum alkaline phosphatase a month befor
e the appearance of hyperirritability and soft tissue swelling about t
he hip joints. The condition gradually resolved during the following e
ight months.