Temperature measurements of fluid in tubing is common practice in many
applications of biology and medicine for the purpose of temperature c
ontrol, analysis, and modeling. Thermocouples are commonly applied for
those measurements and, ignoring the thermal interaction between the
thermocouple and the fluid, it is widely assumed that the thermocouple
's tip reads the undisturbed fluid temperature. The current report pro
vides a simple and explicit formulation for the estimation of the effe
ct of this thermal interaction on the measured temperature value. Resu
lts show that this thermal effect, between the sensor and the sensed p
henomenon, may result in an uncertainty in measurements which overwhel
ms uncertainties from other sources.