M. Monsieurs et al., REAL-LIFE RADIATION BURDEN TO RELATIVES OF PATIENTS TREATED WITH I-131 - A STUDY IN 8 CENTERS IN FLANDERS (BELGIUM), European journal of nuclear medicine, 25(10), 1998, pp. 1368-1376
In view of the EURATOM 96/29 [1] regulations, a prospective multicentr
e study was performed to evaluate the present guidelines given to rela
tives of patients treated with iodine-131 for both thyroid carcinoma a
nd thyrotoxicosis, based on the real-life radiation burden. This study
comprised 166 measurements carried out on a group of 94 relatives of
65 patients. All relatives wore a thermoluminescent dosemeter (TLD) on
the wrist for 7 days. Sixty-one relatives agreed to wear another TLD
for an additional 7 days. TLD were placed on nine patients' bedside ta
bles. The eight participating centres were arbitrarily divided into th
ree groups according to the period of time they advised their patients
to sleep separately. Groups I, II and III respectively advised their
patients to sleep separately for 0, 7-10 and 14-21 days. The median do
se received by in-living relatives of thyroid carcinoma patients durin
g the 14 days following hospital discharge was 281 mu Sv (doses to inf
inity not calculated); the median dose to infinity received by in-livi
ng relatives of ambulatory treated thyrotoxicosis patients was 596 mu
Sv, as compared with 802 mu Sv for in-living relatives of hospitalised
thyrotoxicosis patients. In general the children of patients received
a significantly (P<0.1) lower mean dose than their partners. For thyr
oid carcinoma patients, only two relatives out of 19 (10%) exceeded th
e EURATOM 96/29 limit of 1 mSv/year. For thyrotoxic patients, 28% of r
elatives exceeded the EURATOM 96/29 limit. but none of them were relat
ives of patients who followed guidelines for 21 days. The results of t
his study indicate that sleeping separately for 7 days, after a period
of hospitalisation of 2-3 days, will usually be sufficient for thyroi
d carcinoma patients. For thyrotoxicosis patients, up to 21 days of sl
eeping separately could be necessary in order to strictly abide by EUR
ATOM 96/29. Therefore, the authors propose the implementation of a non
-rigid dose constraint for people who ''knowingly and willingly'' help
patients treated with I-131, while still following the ALARA principl
e.