The purpose of this article is to determine whether some caffeine user
s endorse clinical indicators of dependence and abuse. We asked 162 ra
ndomly-selected caffeine users generic DSM-IV criteria for dependence,
abuse, intoxication and withdrawal pertaining to their caffeine use i
n the last year via a structured telephone interview. The prevalence o
f endorsement of dependence items was 56% for strong desire or unsucce
ssful attempt to stop use: 50% for spending a great deal of time with
the drug, 28% for using more than intended, 18% for withdrawal, 14% fo
r using despite knowledge of harm, 8% for tolerance and 1% for foregoi
ng activities to use. Seven percent of users met DSM-IV criteria for c
affeine intoxication and, among those who had tried to stop caffeine p
ermanently, 24% met DSM-IV research criteria for caffeine withdrawal.
Test-retest interviews for dependency agreed in 29/30 cases (97%). Eig
ht expert substance abuse clinicians agreed with self-endorsed caffein
e dependence 91% of the time. Our results replicate earlier work and s
uggest that a substantial proportion of caffeine users exhibit depende
nce-like behaviors. Further studies are needed to determine whether su
ch users exhibit a clinically significant syndrome of drug dependence.
(C) 1998 Elsevier Science Ireland Ltd. All rights reserved.