S. Preis et al., FOCAL GREY-MATTER HETEROTOPIAS IN MONOZYGOTIC TWINS WITH DEVELOPMENTAL LANGUAGE DISORDER, European journal of pediatrics, 157(10), 1998, pp. 849-852
We describe 9-year-old monozygotic male twins with a developmental lan
guage disorder of the phonologic-syntactic type and learning difficult
ies. High-resolution MRI revealed bilateral parieto-temporal grey matt
er heterotopias in both twins, on the left more than on the right, and
more pronounced in the more affected twin. This suggests a causal rel
ationship between the heterotopias and the neuropsychological findings
in this twin pair. Conclusion Neuronal migration defects and ensuing
fg cal heterotopias may be causally related to developmental language
disorders.