FOCAL GREY-MATTER HETEROTOPIAS IN MONOZYGOTIC TWINS WITH DEVELOPMENTAL LANGUAGE DISORDER

Citation
S. Preis et al., FOCAL GREY-MATTER HETEROTOPIAS IN MONOZYGOTIC TWINS WITH DEVELOPMENTAL LANGUAGE DISORDER, European journal of pediatrics, 157(10), 1998, pp. 849-852
Citations number
36
Categorie Soggetti
Pediatrics
ISSN journal
03406199
Volume
157
Issue
10
Year of publication
1998
Pages
849 - 852
Database
ISI
SICI code
0340-6199(1998)157:10<849:FGHIMT>2.0.ZU;2-0
Abstract
We describe 9-year-old monozygotic male twins with a developmental lan guage disorder of the phonologic-syntactic type and learning difficult ies. High-resolution MRI revealed bilateral parieto-temporal grey matt er heterotopias in both twins, on the left more than on the right, and more pronounced in the more affected twin. This suggests a causal rel ationship between the heterotopias and the neuropsychological findings in this twin pair. Conclusion Neuronal migration defects and ensuing fg cal heterotopias may be causally related to developmental language disorders.