K. Nagarajan et Pj. Rodrigues, ANOMALOUS COURSE OF THE TANDEM CYCLIZATION OF N-BENZYL-N-HIPPURYLHOMOVERATRYLAMINE - FORMATION OF IMIDAZOISOQUINOLINES, Journal of chemical research. Synopses, (8), 1993, pp. 336-337
Cyclization of N-benzyl-N-hippurylhomoveratrylamine (4) with a mixture
Of POCl3 and P2O5 gave unexpectedly ,6-dihydro-8,9-dimethoxyimidazo[5
,1-a]isoquinoline (7) and its 1-benzyl derivative (6), instead of the
targetted 2,3-dihydro-1 H-benzo[de] [1,7]naphthyridine 3.