Bj. Mcconville et al., NEWER ANTIDEPRESSANTS - BEYOND SELECTIVE SEROTONIN REUPTAKE INHIBITORANTIDEPRESSANTS, The Pediatric clinics of North America, 45(5), 1998, pp. 1157
Major depressive disorder in children and adolescents is a significant
problem and is also predictive indicator of severe longterm difficult
ies. Although the current preference is to use SSRIs rather than TCAs
in the treatment of child and adolescent depression, the hard evidence
for efficacy from controlled studies is minimal. This article present
s an overview of these compounds and leads into a discussion of the mo
st common alternate antidepressants used by practitioners, as well as
some newer developments.