PROTEIN FRAGMENTATION DUE TO SLOW HIGHLY-CHARGED ION IMPACT

Authors
RUEHLICKE C SCHNEIDER D SCHNEICLER M DUBOIS RD BALHORN R
Citation
C. Ruehlicke et al., PROTEIN FRAGMENTATION DUE TO SLOW HIGHLY-CHARGED ION IMPACT, Nanotechnology (Bristol. Print), 9(3), 1998, pp. 251-256
Citations number
8
Categorie Soggetti
Engineering,"Physics, Applied","Material Science
Journal title
Nanotechnology (Bristol. Print) → ACNP
ISSN journal
09574484
Volume
9
Issue
3
Year of publication
1998
Pages
251 - 256
Database
ISI
SICI code
0957-4484(1998)9:3<251:PFDTSH>2.0.ZU;2-7
Abstract
We present first results of experiments on the fragmentation of biomol ecules using highly charged heavy ions. Fragmentation and modification of oligopeptides, such as dimerization and attachment of ionic salt c omponents, have been observed by means of mass spectrometry. Plasmid D NA molecules were imaged with an atomic force microscope after ion irr adiation and profound molecular damage was found.