AGREEMENT BETWEEN PREDICTED RISK AND PREVALENCE OF DOWN-SYNDROME IN 2ND-TRIMESTER TRIPLE-MARKER SCREENING IN JAPAN

Authors
ONDA T TANAKA T TAKEDA O KITAGAWA M KUWABARA Y YAMAMOTO H IINUMA K SHIMOMURA K
Citation
T. Onda et al., AGREEMENT BETWEEN PREDICTED RISK AND PREVALENCE OF DOWN-SYNDROME IN 2ND-TRIMESTER TRIPLE-MARKER SCREENING IN JAPAN, Prenatal diagnosis, 18(9), 1998, pp. 956-958
Citations number
7
Categorie Soggetti
Genetics & Heredity","Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
18
Issue
9
Year of publication
1998
Pages
956 - 958
Database
ISI
SICI code
0197-3851(1998)18:9<956:ABPRAP>2.0.ZU;2-O
Abstract
Based on 9350 pregnant Japanese women who were screened by serum tripl e-marker determination, accuracy of predicted risk for Down syndrome w as examined using 24 Down syndrome cases detected either prenatally or postnatally. The correlation is statistically very high (r=0.98) betw een the predicted risks and the prevalence of Down syndrome cases. Her e we emphasize that this could be accomplished only by an extensive fo llow-up study, implemented in our prospective intervention programme. (C) 1998 John Wiley & Sons, Ltd.