A qualitative study was conducted with 28 men and women in HIV-serodis
cordant couples to explore the management of HIV in their relationship
. Content analysis of the interviews revealed the role of serostatus a
nd stigma in shaping partners' experience of HIV, sex and risk. Partne
rs' differing serostatus often created feelings of alienation within t
he relationship. Compounding this interpersonal dynamic, the HIV servi
ce community was experienced as segregating because they were not fund
ed or prepared to work with seronegative partners. Thus many, particul
arly seronegative women, felt invisible both within and outside of the
relationship. Yet, the uninfected partners shared the burden of a sti
gmatizing illness because of the serodiscordant relationship. Stigma h
indered communication about HIV and sex, disclosure to others and acce
ss to services. Many experienced HIV as a loss of their sexuality. Ser
onegative partners spoke about 'keeping sex alive' and often had to pu
sh to continue having sex. Couples used multiple strategies to manage
HIV, including developing strict behavioural guidelines, connecting wi
th other couples, accessing scientific information and becoming educat
ors and activists. These altruistic activities, which also included pa
rticipation in research, helped to transcend external and internalized
stigma. Implications for developing interventions for HIV-serodiscord
ant couples are discussed.