U. Meiners et al., A GENERAL-ROUTE TO THE MONOMERIC SUBUNITS OF THE MACROTETROLIDES - A SHORT SYNTHESIS OF METHYL NONACTATE, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (10), 1998, pp. 2073-2078
A highly stereoselective and flexible sultone route to actic acids, th
e monomeric subunits of the macrotetrolides, has been developed and ex
emplified for nonactic acid (2a). Due to the extensive application of
tandem transformations, only six steps were needed to secure methyl no
nactate (20) from furan.