Objective. To summarize the state of the art in quality improvement, r
eview its application to care for children, and define the information
that will be needed so that care for children can be further improved
. Principal Findings. Health services for children exhibit numerous de
ficiencies in quality of care. The deficiencies cross all major domain
s of pediatric care-preventive services, acute care, and chronic care-
and provide the opportunity for creative application of improvement st
rategies with a potential to benefit the health and well-being of chil
dren. Approaches to quality improvement have changed over the past two
decades from those emphasizing the inspection of structural aspects o
f care and the imposition of sanctions to more dynamic strategies that
emphasize measurement and comparison to motivate change; the use of e
vidence to specify aims for improvement; and the adoption of a variety
of management strategies adapted from business and the social science
s to achieve these aims. These modern approaches to quality improvemen
t have rarely been subjected to rigorous testing of their effectivenes
s. Moreover, their application in pediatrics has been less widespread
than in adult healthcare. For children, several aspects about health s
ervices, such as the relative rarity of chronic illness, the important
effects of social factors on health, and the limited cost, make some
of these approaches even more challenging and may require new approach
es or meaningful modifications. Recommendations. Research to understan
d better the general process of improvement will benefit improvement e
fforts for children. Research that builds the base of knowledge about
best practices for children-effectiveness research-will also result in
an enhanced capacity for improvement of those systems that care for c
hildren's health. Quality of care for children would be enhanced by ta
rgeted research examining ways both to foster improvement across segme
nts of society, and to make recommendations for care more sensitive to
children's development and environmental context. Research that suppo
rts incorporating the child's perspective into care is both uniquely c
hallenging to perform and central to improving pediatric care.