ARYL PHOSPHATE DERIVATIVES OF 3'-DEOXYTHYMIDINE ARE NOT POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS

Authors
VIG R VENKATACHALAM TK JAN ST UCKUN FM
Citation
R. Vig et al., ARYL PHOSPHATE DERIVATIVES OF 3'-DEOXYTHYMIDINE ARE NOT POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS, Antiviral chemistry & chemotherapy, 9(5), 1998, pp. 439-443
Citations number
12
Categorie Soggetti
Virology,"Pharmacology & Pharmacy",Biology
Journal title
Antiviral chemistry & chemotherapy → ACNP
ISSN journal
09563202
Volume
9
Issue
5
Year of publication
1998
Pages
439 - 443
Database
ISI
SICI code
0956-3202(1998)9:5<439:APDO3A>2.0.ZU;2-W
Abstract
Aryl phosphate derivatives of 3'-deoxythymidine (3dT), albeit more act ive than 3dT in thymidine kinase (TK)-deficient cells, are not potent antihuman immunodeficiency virus (HIV) agents and are capable of inhib iting HIV replication only at micromolar concentrations.