THE ROLE OF LIVER-TRANSPLANTATION IN CYSTIC-FIBROSIS

Aim of the study is to evaluate the role of liver transplantation in m odifying CF liver disease patient outcome. Since April 1996 four patie nts affected by hepatic cirrhosis and severe portal hypertension under went liver transplantation. Post-transplant immunosuppression was base d on Neoral with steroids withdrawn in 3 months period. We have never observed mortality of major complications related to surgery. Liver tr ansplantation, in our experience provided in all cases a progressive i mprovement of patient respiratory function, nutritional status and qua lity of life.