HELICOBACTER-PYLORI AS A PATHOGENIC FACTOR IN MENETRIERS-DISEASE

The cause of Menetrier's disease is unknown, although various autoimmu ne, allergic, and infective causes have been postulated. This case rep ort describes a 37-yr-old man with MCnetrier's disease associated with protein-losing enteropathy and Helicobacter pylori infection. Clinica l, endoscopic, histological, and biochemical resolution occurred after treatment of Helicobacter pylori infection, The improvement observed in this case supports an etiological role for H, pylori infection in M enetrier's disease. (Am J Gastroenterol 1998;93: 1976-1979, (C) 1998 b y Am. Cell. of Gastroenterology).