Objective: To evaluate the efficacy and safety of a combined approach
to the treatment of biliary pancreatitis using laparoscopic cholecyste
ctomy and selective endoscopic retrograde cholangiopancreatography (ER
CP). Design: Consecutive case series. Setting: Tertiary care center. P
atients: All patients undergoing primary operations for biliary pancre
atitis during 2 time periods were included. In the open era (June 1982
through May 1988), there were 276 patients; in the laparoscopic era (
January 1996 through June 1997), there were 114 patients. Intervention
s: Open cholecystectomy with or without common bile duct exploration (
CBDE); laparoscopic cholecystectomy with selective ERCP and/or laparos
copic CEDE. Main Outcome Measures: Two periods were compared for morbi
dity, mortality, the duration of preoperative and postoperative stays,
and the total length of hospitalization. Results: Both groups were de
mographically similar and had the same mortality (1.9%). Laparoscopic
cholecystectomies provided a preoperative stay comparable to open chol
ecystectomy (6.4 vs 5.8 days), a shorter postoperative stay (1.5 vs 8.
5 days), a lower incidence of CEDE (6.6% vs 26%), and a lower morbidit
y (8% vs 13.7%). The addition of an ERCP to laparoscopic cholecystecto
my was associated with prolongation of the preoperative stay (7.4 vs 5
.0 days), a comparable postoperative stay, a lower conversion rate (7.
5% vs 13%), and fewer CBDEs (3% vs 13%). In 27 (42%) of the 64 ERCP ca
ses, no stones were found. Conclusions: Treatment of biliary pancreati
tis with combined laparoscopic cholecystectomy and selective ERCP is s
afe and effective and is associated with a shorter hospitalization and
fewer CBDEs than open cholecystectomy. Unnecessary ERCPs can be reduc
ed by improved selection criteria or greater dependence on operative C
EDE.