We report two cases of Aspergillus spondylodiscitis. In the first case
, the origin of contamination is a traumatic inoculation in an immunoc
ompetent patient; the pathogen agent is Aspergillus fumigatus; the pat
ient was first treated with itraconazole, then amphotericin B. In the
second case, it was an hematogenous dissemination in an immunocompromi
sed host; the causative agent was Aspergillus terreus; beside, the fun
gus was also isolated from one of the blood cultures; amphotericin B a
nd itraconazole were used in association. In addition to the antifunga
l therapy a surgical treatment was necessary for healing in both cases
.