ELASMOBRANCH FISH (SCYLIORHINUS-CANICULA AND RAJA-CLAVATA) MUSCLE AMP-DEAMINASE - SUBSTRATE-SPECIFICITY AND EFFECT OF EDTA AND ADENYLATE ENERGY-CHARGE

Authors
IZEM L RAFFIN JP THEBAULT MT
Citation
L. Izem et al., ELASMOBRANCH FISH (SCYLIORHINUS-CANICULA AND RAJA-CLAVATA) MUSCLE AMP-DEAMINASE - SUBSTRATE-SPECIFICITY AND EFFECT OF EDTA AND ADENYLATE ENERGY-CHARGE, Comparative biochemistry and physiology. B. Comparative biochemistry, 106(2), 1993, pp. 383-386
Citations number
33
Categorie Soggetti
Biology
Journal title
Comparative biochemistry and physiology. B. Comparative biochemistry → ACNP
ISSN journal
03050491
Volume
106
Issue
2
Year of publication
1993
Pages
383 - 386
Database
ISI
SICI code
0305-0491(1993)106:2<383:EF(ARM>2.0.ZU;2-W
Abstract
1. The AMP deaminases from skeletal muscles of dogfish and skate were shown to be specific to 5'-AMP. Among several adenine nucleotide analo gs, only dAMP was deaminated to an extent lower than 5%. 2. Similar to vertebrates AMP deaminases, these enzymes were inhibited when incubat ed in the presence of EDTA solutions. 3. The activity of the enzymes w as regulated by adenylic energy charge variations, depending on the si ze of the total adenine nucleotide pool. 4. The shape of the adenylate energy charge response curves of the dogfish and skate muscle AMP dea minases do not distinguish the two enzymes.