D. Canovas et al., SYNTHESIS OF GLYCINE BETAINE FROM EXOGENOUS CHOLINE IN THE MODERATELYHALOPHILIC BACTERIUM HALOMONAS-ELONGATA, Applied and environmental microbiology (Print), 64(10), 1998, pp. 4095-4097
The role of choline in osmoprotection in the moderate halophile Halomo
nas elongata has been examined. Transport and conversion of choline to
betaine began immediately after addition of choline to the growth med
ium. Intracellular accumulation of betaine synthesized from choline wa
s salt dependent up to 2.5 M NaCl. Oxidation of choline was enhanced a
t 2.0 M NaCl in the presence or absence of externally provided betaine
. This indicates that the NaCI concentration in the growth medium has
major effects on the choline-betaine pathway of H. elongata.