Afpk. Leong et al., DIMINUTIVE CANCERS OF THE COLON AND RECTUM - COMPARISON BETWEEN FLAT AND POLYPOID CANCERS, International journal of colorectal disease, 13(4), 1998, pp. 151-153
A comparative study of polypoid and flat colorectal cancers less than
20 mm in size was made. A review of the characteristics of 56 polypoid
cancers and 29 flat cancers treated between April 1989 and January 19
96 was performed. Both groups of cancers showed similar age and locati
on distribution. Polypoid cancers were more likely to be well differen
tiated (38%) than were flat cancers (17%) (P<0.05). Flat cancers were
more likely to have reached the serosa (52% vs 12%; P<0.01) and also d
em demonstrated a higher frequency of lymph node involvement (41% vs p
9%) (P<0.01) when compared to polypoid cancers. Flat colorectal cance
rs belong to a distinct subset which demonstrates greater biological a
ggressiveness than polypoid cancers of equivalent size.