SELECTIVE OXIDATION OF PENICILLIN-G WITH HYDROGEN-PEROXIDE AND WITH ENZYMATICALLY GENERATED PEROXYOCTANOIC ACID

Authors
DEZOETE MC VANRANTWIJK F MAAT L SHELDON RA
Citation
Mc. Dezoete et al., SELECTIVE OXIDATION OF PENICILLIN-G WITH HYDROGEN-PEROXIDE AND WITH ENZYMATICALLY GENERATED PEROXYOCTANOIC ACID, Recueil des travaux chimiques des Pays-Bas, 112(7-8), 1993, pp. 462-463
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Recueil des travaux chimiques des Pays-Bas → ACNP
ISSN journal
01650513
Volume
112
Issue
7-8
Year of publication
1993
Pages
462 - 463
Database
ISI
SICI code
0165-0513(1993)112:7-8<462:SOOPWH>2.0.ZU;2-M
Abstract
Two convenient procedures for the oxidation of penicillin G into penic illin G 1-(s)-oxide have been developed. Both the mild oxidation with enzymatically generated peroxyoctanoic acid and the attractive and sim ple oxidation with the sole use of hydrogen peroxide are valuable alte rnatives for the commercial oxidation with 40% peroxyacetic acid.