POLYMER-SUPPORTED SOLUTION SYNTHESIS OF A HEPTAGLUCOSIDE HAVING PHYTOALEXIN ELICITOR ACTIVITY

Authors
VERDUYN R VANDERKLEIN PAM DOUWES M VANDERMAREL GA VANBOOM JH
Citation
R. Verduyn et al., POLYMER-SUPPORTED SOLUTION SYNTHESIS OF A HEPTAGLUCOSIDE HAVING PHYTOALEXIN ELICITOR ACTIVITY, Recueil des travaux chimiques des Pays-Bas, 112(7-8), 1993, pp. 464-466
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Recueil des travaux chimiques des Pays-Bas → ACNP
ISSN journal
01650513
Volume
112
Issue
7-8
Year of publication
1993
Pages
464 - 466
Database
ISI
SICI code
0165-0513(1993)112:7-8<464:PSSOAH>2.0.ZU;2-W
Abstract
An efficient synthesis of methyl heptaglucoside 2 using poly(ethyleneg lycol)monomethyl ether as a polymer support is described. Elongation o f the acceptor 11, anchored via a succinoyl linkage to PEG, with the a ppropriate glycosyl donors 4-6 and intermittent protective group manip ulations gave fully protected heptamer 18. Deprotection of 18 furnishe d, after purification as its peracetate, title compound 2 in a good ov erall yield.