Lr. Espinoza et al., INSIGHTS INTO THE PATHOGENESIS OF PSORIASIS AND PSORIATIC-ARTHRITIS, The American journal of the medical sciences, 316(4), 1998, pp. 271-276
Psoriasis and its related arthritis are chronic inflammatory disorders
affecting predominantly the skin and synovium. Although their etiolog
y remains to be established, multiple factors seem to play important r
oles in their pathogenesis. These environmental (eg, infectious agents
and trauma), genetic, and immunologic factors are reviewed in this ar
ticle.