INTRACORONARY RADIATION WITH A P-32 SOURCE WIRE

The Proliferation REduction with Vascular ENergy Trial (PREVENT) is a prospective randomized study of the safety and efficacy of intracorona ry brachytherapy to reduce restenosis. A p-emitter. P-32, is embedded on a wire tip and delivered to the target site through a centering cat heter immediately following a coronary intervention. The radiation dos es are 16, 20, and 24 Gy measured at 1 mm within the vessel wall. Foll ow-up includes an angiogram and NUS at 6 months. Phase I of this trial has been completed with results expected in early 1999.