Irreversible thermodynamics in capillary electrophoresis separation process and optimal control

In this paper, on the basis of nonequilibrium thermodynamics separation the ory, the separation model of capillary electrophoresis is established. Taki ng the operating voltage U as controllable parameter, the? net separation e ntropy S-S of solute system as objective function,by optimal design of the separation big system, the optimizing control orbit U* (t) can be obtained. By simulation, the separation efficiency of the system under the control o f U* (t) can reach to the expected results.