Granulomatous mycosis fungoides - Report of a case with some histopathologic features of granulomatous slack skin

We describe a case of granulomatous mycosis fungoides, tumor stage, mimicki ng sarcoidosis in an 82-year-old man with a 2-year history of skin disease. The final diagnosis was established after one of seven biopsy specimens sh owed a nongranulomatous histologic picture of patch-stage mycosis fungoides . Monoclonality was proven for the lymphocytic population by T-cell-recepto r rearrangement studies. The unusually extensive granulomatous inflammation with huge giant cells surrounded by CD1a-positive cells in the other six b iopsy specimens was suggestive of the histopathology of granulomatous slack skin, another rare granulomatous cutaneous T-cell lymphoma. Because both a clinical and histologic overlap between granulomatous mycosis fungoides an d granulomatous slack skin have been reported in the literature, we conclud e that they may belong to the spectrum of a single disease.