Brain morphology and response to nortriptyline in geriatric depression

Authors
Young, RC Kalayam, B Nambudiri, DE Kakuma, T Alexopoulos, GS
Citation
Rc. Young et al., Brain morphology and response to nortriptyline in geriatric depression, AM J GER PS, 7(2), 1999, pp. 147-150
Citations number
17
Categorie Soggetti
Psychiatry
Journal title
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
ISSN journal
10647481 → ACNP
Volume
7
Issue
2
Year of publication
1999
Pages
147 - 150
Database
ISI
SICI code
1064-7481(199921)7:2<147:BMARTN>2.0.ZU;2-W
Abstract
In geriatric patients with major depression (N = 15), the authors compared response to treatment with nortriptyline as it elates to brain morphology a ssessed by computed tomography. There was a significant negative associatio n between ventricle-brain ratio and response to nortriptyline (r(s) = -0.63 ; P = 0.015).