Bacillus popilliae, a fastidious, aerobic, gram-positive, spore-forming bac
illus, has never been reported as a pathogen in human infectious diseases.
We report the first case of a human infected by the pathogen B. popilliae,
which presented as endocarditis involving the bicuspid aortic valve and com
plicated with prolonged (> 30 days; to our knowledge, the longest in the li
terature) complete heart block, Although surgery may be warranted by previo
us reports, the patient was successfully managed by medical treatment inste
ad, because of the absence of evidence from various approaches that support
the existence of perivalvular extension of infection.