Molecularly imprinted electrosynthesized polymers: New materials for biomimetic sensors

The preparation and characterization of electrosynthesized poly(o-phenylene diamine) (PPD) imprinted by glucose (iPPD) is reported as the first case of an electrosynthesized polymer molecularly imprinted by a neutral template. The material is employed as the recognition element of a QCM biomimetic se nsor for glucose. Scatchard analysis of the relevant calibration curve offe rs information on the equilibrium and binding sites involved in glucose det ection. XPS comparison of PPD and iPPD supports the occurrence of a templat ing effect. On this basis, molecular imprinting electropolymerization is pr oposed as a possible strategy for the preparation of new materials with mol ecular recognition properties to be applied in biomimetic sensors.