Traditional risk factors for coronary heart disease (CHD) include only the
patient's age and family history and whether there is evidence of hypertens
ion, elevated LDL, low HDL, diabetes or history of smoking. In recent years
, considerable progress has been made in identifying a new generation of ri
sk factors, including Lp(a), triglycerides, subfractions of HDL and LDL, mo
dified LDL, apo E pheno/genotype, homocysteine and fibrinogen. At the same
time, studies have broadened our knowledge of traditional markers. These ad
vances have enabled physicians to make a better assessment of patient risk
for CHD and to prescribe more appropriate treatment.